ASUS S5 MINI TOWER S501MER
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ASUS S5 Mini Tower

Create. Produce. Play.

An ASUS S501MER is placed on a wooden table, with a monitor placed on its left-hand side.
ASUS S501MER is a potent, elegant and adaptable desktop PC for a variety of applications, spanning everyday content production, remote work, online education and casual gaming. It boasts the latest 14th Generation Intel® Core™ processor and high-performance discrete graphics, paired with two-way AI noise reduction and an efficient cooling system to keep things quick, clear and cool. Crafted with exceptional durability, you’re assured years of dependable computing, and its eye-catching geometric design imparts a modern touch that complements any contemporary home decor.

Productivity

Powerful performance, whatever the task

ASUS S501MER effortlessly handles your workload, featuring a state-of-the-art 14th Gen Intel® Core™ processor that provides ample power for productivity. It also offers the option of professional-grade graphics cards to tackle demanding graphics-intensive assignments. Even without an additional graphics card, you can simultaneously utilize up to three displays. Backed by up to 64 GB DDR5 memory, you can smoothly multitask while running diverse applications and handling your files — with performance that continually impresses.
An ASUS S501MER is shown next to three adjacent displays that are powered by the computer.
Windows 11 Home
 
14th Gen
Intel® CPU
Up to
64 GB
DDR5 RAM
Up to
2 TB + 2 TB
HDD + SSD

Graphics

Professional-grade graphics

Designed for professionals, ASUS S501MER gives you a wide range of professional graphics choices. From video editing to 3D modeling, select your choice of discrete graphics to empower your creativity.
An ASUS S501MER shown next to a monitor.
Realize your full potential with Intel UHD Graphics
ASUS S501MER is available with Intel UHD Graphics 770, ushering in a higher echelon of graphics of graphics performance and crisp, stunning visuals — adding up to accelerated performance and efficiency for content creation, video editing and more.
An ASUS S501MER shown next to a monitor.
Elevate your craft with NVIDIA graphics
ASUS S501MER is available with professional-grade NVIDIA® GeForce RTX™ 4060TI graphics — based on the cutting-edge NVIDIA Turing™ architecture — to help you seamlessly and effortlessly edit your creations and multilayered files, whether you’re creating short online videos, full-length features, animation or 3D modeling, or exploring graphic design. Render quicker, broadcast clearer and edit videos better with NVIDIA GPUs in Studio desktops.

Storage

Dual drives for fast, high-capacity storage

The dual-storage configuration offers the perfect balance by combining the lightning-fast data access speeds of an SSD with the extensive storage capacity of an HDD. This setup allows you to enjoy both high productivity and efficiency, enabling rapid file access within seconds while effortlessly accommodating large files, applications, and media libraries.
A man editing and color grading video through looking at the monitors that are power by an ASUS S501MER on his right-hand side.
Up to
2 TB + 2 TB
PCIe® x4 SSD + HDD

Video Conference

Next-level AI noise-canceling audio technology

For professional conferencing experiences, ASUS S501MER employs AI-powered noise-canceling technology that leverages advanced machine-learning methods. This technology encompasses both an upstream feature for filtering out ambient noise around the speaker and a downstream component to eliminate noise from the remote conversation participant. This guarantees minimal distractions and facilitates high-quality communication, creating an immersive experience that’s just like being in the room with others.
A man is learning lesson through looking at monitors that are powered by an ASUS S501MER on his right-hand side.

Gaming

Fast and fluid

Smooth, clear graphics are crucial in esports, where reaction times make or break plays. ASUS S501MER has an up to an NVIDIA® GeForce RTX™ 4060TI graphics card to pump out reliably high frame rates for fast and fluid gameplay.
A man is playing video game through the monitor that is powered by an ASUS S501MER on his left-hand side.
Up to
GeForce® RTX™ 4060TI
NVIDIA® graphics

Design

The PC that’s part of your décor

Every element of ASUS S501MER has been meticulously considered to achieve a harmonious design. Its distinctive aesthetics draw inspiration FROM geometric architecture, featuring a contemporary 3D triangular pattern and intricate texture to complement any interior space — and is ideal for the home or small studio. This design is more than good looks: the tilted chassis promotes airflow through the base, improving cooling for smooth performance even under heavy loads.
A front view of the ASUS S501MER is shown against a geometric backdrop.
Side view of an ASUS S501MER with cold air flowing from the side into the fan and air chamber while waste heat flowing out, exiting from the back of the chassis.
Less heat, more productivity
For dependable and sustained high performance required in content creation, multitasking, and gaming, an all-encompassing cooling system is crucial. ASUS S501MER achieves superior cooling efficiency through intelligent component positioning, which reduces the gap between the CPU and system fans. The tilted chassis further aids airflow through the base, surpassing competing designs in cooling capabilities and maintaining optimal temperature levels —allowing for higher processor clocks and frequencies and enhanced overall performance.
An ASUS motherboard in black and a CPU highlighted in orange overlay in the center.
World’s #1 motherboards1
All ASUS PCs use ASUS motherboards — the world’s #1 motherboard brand — which are renowned for offering comprehensive system protection to safeguard hardware, 24/7 stability through extensive testing, and consistent performance.
Bar chart comparing the power usage between 80 PLUS and 80 PLUS Bronze-certified devices.
The power wasted by an 80 PLUS Bronze-certified device is 15% of its total power consumption, and this is 5% lower than standard 80 PLUS-certified device.
Power up everything
ASUS S501MER features a high-efficiency 80 PLUS® Bronze-certified power supply. Engineered with top-end capacitors for maximum durability, this enables the PC to deliver power at an efficiency of up to 85% — resulting in less heat and lower long-term running costs.
Nine gold-colored solid capacitors in two runs, running diagonally from the bottom left to top-right corner.
Industry-leading MTBF
All ASUS PCs offer 100% solid capacitors, which are important for storing charge and regulating voltage. This increases system stability, thermal capacity and longevity, resulting in a top-tier Mean Time Between Failures (MTBF) rating.

Connectivity

Comprehensive, hassle-free connections

With a total of eight USB ports, ASUS S501MER makes it easy to upload and transfer files or connect to external devices. Four front-mounted ports make it even more convenient for you to hook up external drives, cameras, or mobile devices without having to reach around the back of the PC.
The front and rear of ASUS S501MER is shown, with all the ports and connections labelled. From top to bottom, left to right. On the back side, there are PS/2 Mouse port, PS/2 Keyboard port, Display port, HDMI port, VGA port, 2 USB 3.1 Gen1 port, LAN (PJ-45) port, 2 USB 2.0 port, Microphone port, Line out port, Line in port, Parallel port, Serial port. On the front side, there are Optical disk driver bay, Microphone port, Headphone port, 2 USB2.0 port, an 3 USB 3.2 Gen1 portsplus USB Type-C.

Reliability

Built for the long term

ASUS desktop PCs are subjected to a series of rigorous noise, vibration, drop and thermal-shock tests to ensure they meet our exacting standards, and exceed those set by other manufacturers. Rest assured that ASUS S501MER can cope with temperature extremes and the bumps and knocks of shipping.
Shock Test
Vibration Test
Altitude Storage Test
Altitude Test
High Temperature Test
High Temperature Storage Test
Low Temperature Test
Low Temperature Storage Test
Humidity Test
  1. ASUS secured the #1 spot for motherboard market share as of 2017, with DigiTimes reporting that the Taiwanese PC component giant owns 45% of the motherboard market.